Michael Nash - NCCR MSE

Michael Nash

Department of Chemistry, University of Basel

Project Leader

Publications

J. Fernandez de Santaella, N. G. Koch, L. Widmer, M. Nash “Amber Codon Mutational Scanning and Bioorthogonal PEGylation for Epitope Mapping of Antibody Binding Sites on Human Arginase-1“ ACS Chem. Biol. 2025. [DOI]
M. Heiniger, R. Vanella, Z. Walsh-Korb, M. Nash “Functionalized Polysaccharides Improve Sensitivity of Tyramide/Peroxidase Proximity Labeling Assays through Electrostatic Interactions“ ACS Biomater. Sci. Eng. 2024. [DOI]
H. Liu, A. M. Vera, B. Yang, P. Tinnefeld, M. Nash “Engineering an artificial catch bond using mechanical anisotropy“ Nat. Commun. 2024. [DOI]
R. Vanella, C. Kung, A. A. Schoepfer, V. Doffini, J. Ren, M. Nash “Understanding activity-stability tradeoffs in biocatalysts by enzyme proximity sequencing“ Nat. Commun. 2024. [DOI]
Z. Liu, M. Sa Santos, M. Nash “Direct Comparison of Lysine versus Site-Specific Protein Surface Immobilization in Single-Molecule Mechanical Assays**“ Angew. Chem. Int. Ed. 2023. [DOI]
J. Lopez-Morales, R. Vanella, T. Utzinger, V. Schittny, J. Hirsiger, M. Osthoff, C. T. Berger, Y. Guri, M. Nash “Multiplexed on-yeast serological assay for immune escape screening of SARS-CoV-2 variants“ iScience 2023. [DOI]
J. Fernández De Santaella, J. Ren, R. Vanella, M. Nash “Enzyme Cascade with Horseradish Peroxidase Readout for High-Throughput Screening and Engineering of Human Arginase-1“ Anal. Chem. 2023. [DOI]
J. Lopez-Morales, R. Vanella, G. Kovacevic, M. S. Santos, M. Nash “Titrating Avidity of Yeast-Displayed Proteins Using a Transcriptional Regulator“ ACS Synth. Biol. 2023. [DOI]
F. Risser, J. López-Morales, M. Nash “Adhesive Virulence Factors of Staphylococcus aureus Resist Digestion by Coagulation Proteases Thrombin and Plasmin“ ACS Bio. Med. Chem. Au 2022. [DOI]
Z. Liu, B. Yang, J. Lopez Morales, M. Nash “Optimal Sacrificial Domains in Mechanical Polyproteins: S. epidermidis Adhesins Are Tuned for Work Dissipation“ JACS Au 2022. [DOI]
R. Vanella, G. Kovacevic, V. Doffini, J. Fernández de Santaella, M. Nash “High-throughput screening, next generation sequencing and machine learning: advanced methods in enzyme engineering“ Chem. Commun. 2022. [DOI]
H. Liu, R. A. Moreira, A. Dujmović, B. Yang, A. B. Poma, M. Nash “Mapping Mechanostable Pulling Geometries of a Therapeutic Anticalin/CTLA-4 Protein Complex“ Nano Lett. 2022. [DOI]
M. S. Santos, H. Liu, V. Schittny, R. Vanella, M. Nash “Correlating Single-molecule Rupture Mechanics with Cell Population Adhesion by Yeast Display of Monomeric Streptavidin“ Biophys. Rep. 2021. [DOI]
B. Yang, Z. Liu, R. Doenen, M. Nash “Influence of Fluorination on Single-Molecule Unfolding and Rupture Pathways of a Mechanostable Protein Adhesion Complex“ Nano Lett. 2020. [DOI]
H. Liu, V. Schittny, M. Nash “Removal of a Conserved Disulfide Bond Does Not Compromise Mechanical Stability of a VHH Antibody Complex“ Nano Lett. 2019. [DOI]
H. Liu, D. T. Ta, M. Nash “Mechanical Polyprotein Assembly Using Sfp and Sortase-Mediated Domain Oligomerization for Single-Molecule Studies“ Small Methods 2019. [DOI]
R. Vanella, D. T. Ta, M. Nash “Enzyme-mediated hydrogel encapsulation of single cells for high-throughput screening and directed evolution of oxidoreductases“ Biotechnol. Bioeng. 2019. [DOI]
R. Vanella, A. Bazin, D. T. Ta, M. Nash “Genetically encoded stimuli-responsive cytoprotective hydrogel capsules for single cells provide novel genotype-phenotype linkage“ Chem. Mater. 2019. [DOI]
D. T. Ta, R. Vanella, M. Nash “Bioorthogonal Elastin-like Polypeptide Scaffolds for Immunoassay Enhancement“ ACS Appl. Mater. Interfaces 2018. [DOI]
H. Liu, D. T. Ta, M. Nash “Mechanical Polyprotein Assembly Using Sfp and Sortase‐Mediated Domain Oligomerization for Single‐Molecule Studies“ Small Methods 2018. [DOI]
D. T. Ta, R. Vanella, M. Nash “Magnetic separation of elastin-like polypeptide receptors for enrichment of cellular and molecular targets“ Nano Lett. 2017. [DOI]