This project focuses on the development of an innovative methodology for the assembly of hierarchical architectures on both solid and polymer platforms. The goal is to design multi-functional systems supporting cascade reactions in 2D networks of nano-compartments (polymersomes, liposomes and combination of thereof) by their controlled anchoring and patterning on surfaces. We will develop strategies and proof-of-principle systems with material turn-over based upon either soft-condensed matter supports (polymers) or hard, metal oxide supports. New soft–hard interfaces will be designed to provide a micro- and nanoscale environment which can modulate properties and activity.