ROS-Probes for Life-Cell Imaging of the Metabolic Activity of Immune Cells - NCCR MSE

ROS-Probes for Life-Cell Imaging of the Metabolic Activity of Immune Cells

Reactive oxygen species (ROS) and reactive nitrogen species are produced in phagolysosomes and play central roles in our immune response, inflammation and healing. Under pro-inflammatory conditions, macrophages upregulate ROS production, which helps them to clear wound sites.

Our goal in this project is to develop tools that allow to probe and quantify ROS levels in the interior of macrophages and of other phagocytes, as well as investigate signalling changes in macrophages in response to ROS stimulation.

Publications

Lab

Vogel group @ETHZ

Palivan group @UniBas