Biomolecular Systems Engineering

Biomolecular Systems Engineering

PI Randall Platt was recently appointed assistant professor by ETH Zurich. He started his research for the NCCR Molecular Systems Engineering in the field of bimolecular systems engineering on 1 October 2016 and will significantly strengthen the expertise in Work Package 4. > more

Articles

G. Wang, R. D. Chow, L. Ye, C. D. Guzman, X. Dai, M. B. Dong, F. Zhang, P. A. Sharp, R. Platt, S. Chen “Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR–mediated direct in vivo screening“ Sci. Adv. (2018). [Link]
R. D. Chow, C. D. Guzman, G. Wang, F. Schmidt, M. W. Youngblood, L. Ye, Y. Errami, M. B. Dong, M. A. Martinez, F. Zhang, P. Renauer, K. Bilguvar, M. Gunel, P. A. Sharp, R. Platt, S. Chen “AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma“ Nat. Neurosci. (2017). [Link]
F. Schmidt, R. PlattApplications of CRISPR-Cas for synthetic biology and genetic recording“ Curr. Opin. Syst. Biol. 5, 9-15 (2017). [Link]
R. Platt, Y. Zhou, I. M. Slaymaker, A. S. Shetty, N. R. Weisbach, J. Kim, J. Sharma, M. Desai, S. Sood, H. R. Kempton, G. R. Crabtree, G. Feng, F. Zhang “Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits“ Cell Rep. 19, 335-50 (2017). [Link]

Who works with whom?

Prof. Randall Platt from the ETH Zürich (Dept. of Biosystems Science and Engineering) leads this project and works with PhD student Maria Kuhn.

Group

Read more about the Platt-Group here